Aeromonas Hydrophila and Related Bacteria Aeromonas hydrophila and Related Bacteria Significance Aeromonas hydrophila(pronounced "air-oh-moan-ass" "high-drof-ill-uh") is abacterium that is commonly found in freshwater environments and in brackishwater. Although there has never been a known outbreak or illness from Aeromonashydrophila, it has been isolated from sprouted seeds. Fortunately, A. hydrophila is susceptible to a 1% solution ofsodium hypochlorite. Though I am unaware of any studies undertaken to remove thepathogen from seed, the FDA recommended 2% solution of calcium hypochlorite as asoak should have an effect on reducing or eliminating this potentially harmfulbacterial from sprouting seed. Some, but not all, strainsof A. hydrophila are capable of causing illness in humans by infectingopen wounds and possibly by ingesting the organisms in food or water. Severalrelated species, Aeromonas caviae, Aeromonas sobria and Aeromonasveroniimay also be capable of causing illness in humans. At the present time, thereis controversy as to whether or not these organisms are able to cause humangastrointestinal illness. Volunteer human feeding studies, even with highnumbers of cells, have not produced illness. However, the organism has beenpresent in the stools of individuals
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Evaluation of Nutritional Availability and Anti Evaluation of Nutritional Availability and Anti-Tumor Activity of Selenium Contained in Selenium-Enriched Kaiware Radish Sprouts. Biosci Biotechnol Biochem. 2007 Sep 7; Yoshida M, Okada T, Namikawa Y, Matsuzaki Y, Nishiyama T, Fukunaga K. Laboratory of Food and Nutritional Sciences, Department of Biotechnology, Faculty of Engineering,KansaiUniversity. We estimated the nutritional availability of selenium (Se) in Se-enriched Kaiware radish sprouts (SeRS) by the tissue Se deposition and glutathione peroxidase (GPX) activity of rats administered the sprouts, and examined the effect of SeRS on the formation of aberrant crypt foci (ACF) in the colon of mice administered 1,2-dimethylhydrazine (DMH) to evaluate anti-tumor activity. Male weanling Wistar rats were divided into seven groups and fed a Se-deficient basal diet or the basal diet supplemented with 0.05, 0.10, or 0.15 mug/g of Se as sodium selenite or SeRS for 28 d. Supplementation with Se dose-dependently increased serum and liver Se concentrations and GPX activities, and the selenite-supplemented groups showed a higher increase than the SeRS-supplemented groups. The nutritional availability
Effects of Pre-Germinated Brown Rice Effects of pre-germinated brown rice on beta-amyloid protein-induced learning and memory deficits in mice. Biol Pharm Bull. 2004 Jul;27(7):1041-5. Mamiya T, Asanuma T, Kise M, Ito Y, Mizukuchi A, Aoto H, Ukai M. Department of Chemical Pharmacology, Faculty of Pharmacy, Meijo University, Nagoya, Japan. We evaluated the effects of pre-germinated brown rice (hatsuga genmai, PGR) on learning and memory and compared them with those of polished rice or cornstarch. In mice that were fed pellets of polished rice or PGR for two weeks, the learning ability in the Morris water maze test was significantly enhanced compared with mice that were fed cornstarch pellets. In the Y-maze test, the intake of food pellets for two weeks failed to affect spontaneous alternation behavior. Beta-amyloid(25-35) (Abeta(25-35): 3 nmol/mouse, i.c.v.) protein impaired spontaneous alternation behavior in mice that were fed pellets of cornstarch or polished rice. In contrast, PGR pellets prevented the Abeta(25-35)-induced impairment of spontaneous alternation behavior. These results suggest that polished rice and PGR have facilitating effects
Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. FoodChem Toxicol. 2009 Jul;47(7):1430-6.Epub 2009 Mar 27. Melchini A, Costa C, Traka M, Miceli N, Mithen R, De Pasquale R, Trovato A. Dip.Farmaco-Biologico,Facoltà di Farmacia, Università di Messina, VillaggioAnnunziata, 98168 Messina,Italy. Erucin (ER) is a dietaryisothiocyanate present in cruciferous vegetables, such as rocket salads (Erucasativa Mill.,Diplotaxis sp.), that has been recently considered a promising cancer chemopreventivephytochemical. Biological activity of ER was investigated on human lung adenocarcinoma A549 cells, analyzing its effects on molecular pathways involved in apoptosis and cell cycle arrest, such as PARP-1 cleavage, p53 and p21 protein expression. Our results show that ER affects the A549 cell proliferation, enhancing significantly p53 and p21 protein expression in a dose-dependent manner (p<0.001). PARP-1 cleavage occurs only after exposure to high concentrations of ER (50 microM), in accordance to previous studies showing similar bioactivity of other isothiocyanates (ITCs). Our study reports for the first time that the induction of p53, p21 and PARP-1
Food sources of phyto-oestrogens and their precursors in Europe. Br J Nutr. 2003 Jun;89 Suppl 1:S39-43. Fletcher RJ. Kellogg Company, Manchester, UK. Phyto-oestrogens are dietary components found in some plants, which act in vivo like weak oestrogens. They may reduce the risk of some degenerative diseases moderated by oestrogen, including breast cancer and osteoporosis. The most widely studied are the isoflavones genistein and daidzein from soyabeans, but lignans may be more prevalent in the European diet. Soya foods have traditionally been consumed in the Orient for millennia, and are now widely available to European consumers. Levels of isoflavone in soyabeans from published literature vary between 560 and 3810 mg/kg, depending on variety and growing conditions. Soya protein concentrates and isolates derived from soyabeans contain 466-615 mg isoflavones/kg. Traditional soya milk, bean curds, bean sprouts, etc. contain 13 to 2030 mg isoflavone/kg, depending on the starting raw material and final water content. Fermented foods have a different isoflavone conjugate profile, which may be important in absorption and metabolism. Soya analogues of European
Germinated Barley Foodstuff Germinated barley foodstuff, a prebiotic product, ameliorates inflammation of colitis through modulation of the enteric environment. J Gastroenterol. 2003;38(2):134-41. Kanauchi O, Serizawa I, Araki Y, Suzuki A, Andoh A, Fujiyama Y, Mitsuyama K, Takaki K, Toyonaga A, Sata M, Bamba T. Nutrient Food and Feed Division, Kirin Brewery Co Ltd, 2-10-1 Shinkawa, Chuo-ku, Tokyo 104-8288, Japan. BACKGROUND: Germinated barley foodstuff (GBF), which contains glutamine-rich protein and hemicellulose-rich fiber, exhibits therapeutic effects in ulcerative colitis; however, its mechanism is still under investigation. The aim of this study was to evaluate the anti-inflammatory effects of GBF on colitis in terms of the epithelial inflammatory response. METHODS: Mice with dextran sulfate sodium-induced colitis were used. The effects of GBF on the colitis were evaluated by measuring the body weight; disease activity; mucosal damage (histology, mucosal inflammatory parameters, nuclear factor kappa B [NFkB] activation, and signal transducer and activator of transcription 3 [STAT3]); serum interleukin 6 (IL-6) level; cecal short-chain fatty acids (SCFAs); and bile acid contents. RESULTS:GBF significantly prevented disease activity