Sprouts and Breast Cancer & Mammary Tumors

The corpus of research about sprouts and breast cancer is constantly expanding. To help guide your search, we’ve gathered the latest studies in a single location.

“Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells.” Toxicol Appl Pharmacol. 2005 Jun 10; Rose P, Huang Q, Ong CN, Whiteman M.

“Cancer-protective properties of high-selenium broccoli.” J Agric Food Chem 2001 May;49(5):2679-83, Finley JW, Ip C, Lisk DJ, Davis CD, Hintze KJ, Whanger PD., Grand Forks Human Nutrition Research Center, Agricultural Research Service, U.S. Department of Agriculture, P.O. Box 9034, Grand Forks, North Dakota 58203-9034, USA.

“Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells.” Exp Biol Med (Maywood). 2009 Mar;234(3):287-95. Epub 2009 Jan 14. Telang U, Brazeau DA, Morris ME. Department of Pharmaceutical Sciences, 517 Hochstetter Hall, University at Buffalo, State University of New York, Amherst, NY 14260-1200, USA.

“Dietary patterns and breast cancer risk in the shanghai breast cancer study.” Cancer Epidemiol Biomarkers Prev. 2007 Jul;16(7):1443-8. Epub 2007 Jul 10. Cui X, Dai Q, Tseng M, Shu XO, Gao YT, Zheng W. Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.

“Evaluation of the estrogenic effects of legume extracts containing phytoestrogens.”J Agric Food Chem. 2003 Apr 9;51(8):2193-9. Boue SM, Wiese TE, Nehls S, Burow ME, Elliott S, Carter-Wientjes CH, Shih BY, McLachlan JA, Cleveland TE. Agricultural Research Service, Southern Regional Research Center, U.S. Department of Agriculture, New Orleans, Louisiana 70179, USA.

“Flaxseed sprouts induce apoptosis and inhibit growth in MCF-7 and MDA-MB-231 human breast cancer cells.” In Vitro Cell Dev Biol Anim. 2012 Mar 22. Lee J, Cho K. Department of Chemistry and Biochemistry, North Dakota State University, Fargo, ND, 58108, USA.

“Food sources of phyto-oestrogens and their precursors in Europe”, Br J Nutr. 2003 Jun;89 Suppl 1:S39-43. Fletcher RJ. Kellogg Company, Manchester, UK.

“Health effects of phytoestrogens” Forum Nutr. 2005;(57):100-11. Branca F, Lorenzetti S. National Institute for Research on Food and Nutrition, Rome, Italy.

“High-Selenium Broccoli Stymies Some Cancers”, Science Update, Agricultural Research Magazine, April 2002.

“Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: Studies with sulforaphane and garlic organosulfur compounds.” Environ Mol Mutagen. 2009 Feb 5. Nian H, Delage B, Ho E, Dashwood RH. Linus Pauling Institute, Oregon State University, Corvallis, Oregon.

“Modulation of markers associated with aggressive phenotype in MDA-MB-231 breast carcinoma cells by sulforaphane.”  Neoplasma. 2009;56(6):548-56. Hunakova L, Sedlakova O, Cholujova D, Gronesova P, Duraj J, Sedlak J. Tumor Immunology Laboratory, Cancer Research Institute, Bratislava, Slovak Republic.

“Molecular Targets and Anticancer Potential of Indole-3-Carbinol and Its Derivatives” Cell Cycle. 2005 Sep 6;4(9), Aggarwal BB, Ichikawa H.

“Preclinical and Clinical Evaluation of Sulforaphane for Chemoprevention in the Breast”Carcinogenesis. 2007 Mar 7; Cornblatt BS, et al. Department of Environmental Health Sciences, The Johns Hopkins University, Baltimore, Maryland 21205.

“Regulation of estrogen receptor alpha expression in human breast cancer cells by sulforaphane.” Ramirez MC, Singletary K. Department of Food Science and Human Nutrition, University of Illinois, Urbana, 61801, USA.

“Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells.” Clin Cancer Res. 2010 May 1;16(9):2580-90. Epub 2010 Apr 13. Li Y, Zhang T, Korkaya H, Liu S, Lee HF, Newman B, Yu Y, Clouthier SG, Schwartz SJ, Wicha MS, Sun D. Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA.

“Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane.” Carcinogenesis. 2008 Dec;29(12):2360-8. Epub 2008 Oct 23. Azarenko O, Okouneva T, Singletary KW, Jordan MA, Wilson L. Department of Molecular, Cellular, and Developmental Biology and the Neuroscience Research Institute, University of California, Santa Barbara, CA 93106, USA.

“Vegetable extracts may aid breast cancer prevention” August 9, 2005, By Keith T. Mead, Special to The Clarion-Ledger.